transformer the deep chemistry of life and death nick lane

Life is at root a chemical phenomenon: this is its deep logic. Enlivened by Lanes talent for distilling and humanizing complex research, Transformer offers an essential read for anyone fascinated by biologys great mysteries. How can the same pathway create and destroy? What might our study of the Krebs cycle teach us about the mysteries of aging and the hardest problem of all, consciousness? Transformer unites the story of our planet with the story of our cells-what makes us the way we are, and how it connects us to the origin of life. Yet this same cycle, spinning in reverse, also created the chemical building blocks that enabled the emergence of life on our planet. Lane reveals the beautiful, violent world within our cells, where hydrogen atoms are stripped from the carbon skeletons of food and fed to the ravenous beast of oxygen.

Transformer is Lanes voyage, as a biochemist, to find the inner meaning of the Krebs cycle-and its reverse-why it is still spinning at the heart of life and death today. Lane is among the vanguard of researchers asking why the Krebs cycle, the perfect circle at the heart of metabolism, remains so elusive more than eighty years after its discovery. In Transformer, biochemist Nick Lane reveals a scientific renaissance that is hiding in plain sight -how the same simple chemistry gives rise to life and causes our demise. Our inheritance also includes our living metabolic network, a flame passed from generation to generation, right back to the origin of life. Information is important, but it is only part of what makes us alive. He is one of my favorite science writers.-Bill Gates Book Synopsis What brings the Earth to life, and our own lives to an end? For decades, biology has been dominated by the study of genetic information. Nick Lanes exploration of the building blocks that underlie lifes big fundamental questions-the origin of life itself, aging, and disease-have shaped my thinking since I first came across his work. About the Book From the renowned biochemist and author of The Vital Question, an illuminating inquiry into the Krebs cycle and the origins of life.

Transformer the deep chemistry of life and death nick lane